Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Tracheal adenoid cystic carcinoma
- Radiologic Findings
- Figs 1. Chest PA shows a small nodule in cervical trachea.
Fig 2-4. Mediastinal window setting of the chest CT scan shows about 9x11x13 mm sized, well-demarcated enhancing polypoid nodule arising from the lateral wall of the cervical trachea.
Fig 5. FDG-PET CT scan reveals a small hypermetabolic nodule in the cervical trachea.
- Brief Review
- Primary tracheal tumors are rare, with an incidence of only 0.2 per 100,000 persons per year. Adenoid cystic carcinoma (ACC) is the second most common type of tracheal malignancy, preceded by squamous cell carcinoma.
ACC is usually first recognized without sex predilection in patients in their 40s, and smoking does not affect the incidence. Symptoms in patients with adenoid cystic carcinoma are usually related to airway obstruction. Dyspnea, cough, stridor, wheezing, and hemoptysis are the most common complaints. ACC usually arises in the lower trachea. Others are found in the mainstem bronchi; lobar bronchi; or, rarely, in the segmental bronchi and extrathoracic trachea.
On CT, the tumor has a striking tendency toward a submucosal extension that manifests as an intraluminal mass of soft-tissue attenuation with extension through the tracheal wall, a diffuse or circumferential wall thickening of the trachea, a soft-tissue mass filling the airway, or a homogeneous mass encircling the trachea with wall thickening in the transverse and longitudinal planes. ACC in the extrathoracic trachea may directly invade the thyroid gland and tracheal cartilages. Distant metastasis occurs late in the disease course.
- References
- 1. Azar, Taraneh, Fadi W. Abdul
- Please refer to
- Case 1267 Case 1229 Case 418 Case 89
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- Keywords
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